Recombinant Mouse IMPAD1/IMP3 Protein (His Tag)

Sizes: 10μg, 50μg

Catalogue Numbers: PKSM041326-10, PKSM041326-50

Citations, Manuals and MSDS Available upon request.

Abbreviation: IMPAD1; IMP3

Target Synonym: Inositol monophosphatase 3; Impad1; IMPA3

UNIProt ID: Q80V26

Target Species: Mouse

Expression Host: HEK293 Cells

Fusion Tag: N-His

Accession: Q80V26

Background: IMPAD1 protein (IMPA3, gPAPP or IMPase 3) belongs to the inositol monophosphatase family. It is found in Purkinje cells, brain stem, lung and chondrocytes. Mouse IMPAD1 gene encodes a type II transmembrane Golgi-embedded glycoprotein with 356 amino acid residues which generates a 306 amino acid residues mature protein after processing. It is expressed in embryo, and in theory may catalyze myo-inositol monophosphate to myo-inositol. Free myo-inositol is used to generate inositol phospholipid, an essential component of intracellular signaling pathways that mobilize calcium. Mouse IMPAD1 exhibits 91% sequence identity with the human homologue.

Sequence: Glu51-His356

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, 10%Glycerol, pH8.0.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: Not Applicable

Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.

Calculated MW: 34.3 kDa

Observed MW: 38 kDa

Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at < - 20°C.

Research Use Only