Cleaved PARP1 Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22074-60, E-AB-22074-120, E-AB-22074-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: Cleaved PARP

Target Synonym: ADP-ribosyltransferase diphtheria toxin-like 1; ADPRT 1; ADPRT; ADPRT1; APOPAIN; ARTD1; NAD(+) ADP-ribosyltransferase 1; PARP; PARP-1; PARP1; PARP1; Poly [ADP-ribose] polymerase 1; Poly ADP ribose polymerase 1; Poly[ADP-ribose] synthase 1; PPOL; SCA1

Research Areas: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human

Application: WB

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:4A3

UNIProt ID: P09874

Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:1000-3000

Observed MW: 116,89kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only