AF/LE Purified Anti-Mouse CD80 Antibody [16-10A1]

Sizes: 500μg, 1mg

Catalogue Numbers: E-AB-F09920-500, E-AB-F09920-1

Citations, Manuals and MSDS Available upon request.

Abbreviation: CD80

Target Synonym: T-lymphocyte activation antigen CD80, Cd80, Activation B7-1 antigen, B7,

Conjugation: None (Purified antibody-Azide Free/Low endotoxin)

Host: Armenian Hamster

Species Reactivity: Mouse

Application: FCM,Block

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype: Armenian Hamster IgG

Clone No.: 16-10A1

UNIProt ID: Q00609

Background: CD80 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD80 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD80 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD80 appears to be expressed later in the immune response than CD86. CD80 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Concentration: 0.5 mg/mL

Control Catalogue Number: E-AB-F098530

Buffer: 0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.

Gene ID: 12519

Storage: This product can be stored at 2-8°C for 12 months. Do not freeze.

Shipping: Ice bag

Research Use Only