AFP Monoclonal Antibody

Sizes: 60μL, 120μL, 200μL

Catalogue Numbers: E-AB-22033-60, E-AB-22033-120, E-AB-22033-200

Citations, Manuals and MSDS Available upon request.

Abbreviation: AFP alpha 1 Fetoprotein

Target Synonym: Afp; AFPD; Alpha fetoglobulin; Alpha fetoprotein; Alpha fetoprotein precursor; Alpha-1-fetoprotein; Alpha-fetoglobulin; Alpha-fetoprotein; alpha-fetoprotein; Hereditary persistence of; included; FETA; FETA; Hereditary persistence of alpha fetoprotein; HPAFP

Research Areas: Cancer, Cardiovascular, Developmental Biology

Conjugation: Unconjugated

Host: Mouse

Species Reactivity: Human

Application: WB, IHC-p, IF

Isotype: IgG

Clonality: Monoclonal

Clone No.: Clone:2L6

UNIProt ID: P02771

Background: This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly.

Concentration: 1 mg/mL

Immunogen: Synthetic Peptide

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Protein A purification

Dilution: WB 1:500-1:3000, IHC 1:50-1:300, IF 1:100-1:300

Observed MW: 70kDa

Storage: -20°C/One year. Avoid freeze / thaw cycles.

Shipping: Ice bag

Research Use Only