Hexokinase I Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11022-50, MB11022-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: P19367

Host: Rabbit

Reactivity: Human, Mouse, Rat

Applications: WB, IHC-F, IHC-P, ICC/IF

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200

Background: Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation.

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 102 kDa; Observed MW: 102 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Immunocytochemistry analysis of Hexokinase I in K562 using Hexokinase I antibody, and DAPI., Western blot analysis of Hexokinase I in K562, rat Brain, 3T3 lysates using Hexokinase I antibody., Immunohistochemistry analysis of paraffin-embedded Human tonsil using Hexokinase I antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Alternative Name: HK1; Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I

Immunogen: A synthetic peptide of human Hexokinase 1

Conjugate: Unconjugated

Modification: Unmodified