HEM1 rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES15793-50, ES15793-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes the mitochondrial enzyme which is catalyzes the rate-limiting step in heme (iron-protoporphyrin) biosynthesis. The enzyme encoded by this gene is the housekeeping enzyme; a separate gene encodes a form of the enzyme that is specific for erythroid tissue. The level of the mature encoded protein is regulated by heme: high levels of heme down-regulate the mature enzyme in mitochondria while low heme levels up-regulate. A pseudogene of this gene is located on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015],

Source: Rabbit

Applications: WB

Dilution: WB 1: 500-2000

Reactivity: Human; Mouse; Rat

Immunogen: Synthesized peptide derived from human HEM1 AA range: 87-137

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Human Gene ID: 211

Human SWISS Prot NO: P13196

Subcellular Location: Mitochondrion inner membrane; Peripheral membrane protein. Localizes to the matrix side of the mitochondrion inner membrane.

Research Use Only