6-O-Caffeoylarbutin (Robustaside B) possesses antioxidant activity.

Product information

CAS Number: 136172-60-6

Molecular Weight: 434.39

Formula: C21H22O10

Chemical Name: [(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-(4-hydroxyphenoxy)oxan-2-yl]methyl (2E)-3-(3,4-dihydroxyphenyl)prop-2-enoate

Smiles: O[C@H]1[C@@H](O[C@H](COC(=O)/C=C/C2=CC(O)=C(O)C=C2)[C@@H](O)[C@@H]1O)OC1C=CC(O)=CC=1

InChiKey: OONDLKCAZJZRCW-CTPWMPFQSA-N

InChi: InChI=1S/C21H22O10/c22-12-3-5-13(6-4-12)30-21-20(28)19(27)18(26)16(31-21)10-29-17(25)8-2-11-1-7-14(23)15(24)9-11/h1-9,16,18-24,26-28H,10H2/b8-2+/t16-,18-,19+,20-,21-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

In the presence of calcium, similar concentrations of robustaside B decreases the extent of MPT pore opening in a concentration-dependent manner but in the reverse order. Robustaside B (0.1mM) and para-hydroxyphenol(0.05mM) significantly inhibits mitochondrial lipid peroxidation induced by the Fe2+/ascorbate system by causing a significant decrease (86.4 and 86.7%), respectively, in the amount of TBARS released by the system.

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