RENT1 Monoclonal Antibody

Sizes: 50µl, 100µl

Catalogue Numbers: MB11529-50, MB11529-100

Product: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

Swiss-Prot: Q92900

Host: Rabbit

Reactivity: Human

Applications: WB, IHC-F, IHC-P, ICC/IF, IP,

All Applications: WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200 IP: 1/20

Background: Plays a role in replication-dependent histone mRNA degradation at the end of phase S. Part of a post-splicing multiprotein complex. Involved in nonsense-mediated decay (NMD) as part of the SMG1C complex, a mRNA surveillance complex that recognizes and degrades mRNAs containing premature translation termination codons (PTCs).

Purification and Purity: Affinity Purified

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: IgG

Bioworld Molecular Weight: Calculated MW: 124 kDa; Observed MW: 124 kDa

Note: For research use only, not for use in diagnostic procedure.

Extra Notes: Western blot analysis of RENT1 / hUPF1 in Jurkat, Hela lysates using RENT1 antibody., Immunohistochemistry analysis of paraffin-embedded Human Cholangiocarcinoma using RENT1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval., Immunocytochemistry analysis of RENT1 in Hela using RENT1 antibody, and DAPI

Alternative Name: UPF1; KIAA0221; RENT1; Regulator of nonsense transcripts 1; ATP-dependent helicase RENT1; Nonsense mRNA reducing factor 1; NORF1; Up-frameshift suppressor 1 homolog; hUpf1

Immunogen: A synthetic peptide of human RENT1

Conjugate: Unconjugated

Modification: Unmodified